BDBM50445335 CHEMBL3104246::US9555024, 6

SMILES COc1ccc(Cl)cc1C(=O)NNC(=O)c1cc(ccc1F)S(=O)(=O)N1CCOCC1

InChI Key InChIKey=KSYNEVQBVXQRCY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50445335   

TargetLysine-specific histone demethylase 1A(Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM50445335(CHEMBL3104246 | US9555024, 6)
Affinity DataIC50: 3.00E+3nMAssay Description:The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM50445335(CHEMBL3104246 | US9555024, 6)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using dimethyl K4 peptide as substrate assessed as resorufin level by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Utah Research Foundation

US Patent
LigandPNGBDBM50445335(CHEMBL3104246 | US9555024, 6)
Affinity DataIC50: 3.00E+3nMAssay Description:The primary assay for compound inhibitory activity was the LSD1 Inhibitor Screening Assay Kit (Cayman Chemical Company, Ann Arbor, Mich.; Cayman Chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent