BDBM50445329 CHEMBL3104242

SMILES C[C@@H]1NC(=O)[C@@H]2CSSC[C@H](NC(=O)CN)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC1=O)C(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N2

InChI Key InChIKey=AIKMSOHWSGWCNX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50445329   

TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of human alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human alpha9alpha10 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 595nMAssay Description:Inhibition of human alpha7 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 41nMAssay Description:Inhibition of human alpha3beta2 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 497nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445329(CHEMBL3104242)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -100 mV holding potential inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed