BDBM50445250 CHEMBL3102859

SMILES c1[nH]c2ncc(cc2c1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=JXEPUZVUZPLZMS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50445250   

LigandPNGBDBM50445250(CHEMBL3102859)
Affinity DataIC50: 410nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Oribase Pharma

Curated by ChEMBL
LigandPNGBDBM50445250(CHEMBL3102859)
Affinity DataIC50: 4.06E+3nMAssay Description:Inhibition of recombinant human His-tagged AXL expressed in insect cells after 60 mins by Z'-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details Article
PubMed
TargetTRAF2 and NCK-interacting protein kinase(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50445250(CHEMBL3102859)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of TNIK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50445250(CHEMBL3102859)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK8 (unknown origin) in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed