BDBM50445242 CHEMBL3102941

SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(-c3ccccc3)c2c1

InChI Key InChIKey=PTKRZXHHLCHSFE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445242   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Upr 2301, Cnrs

Curated by ChEMBL

LigandBDBM50445242(CHEMBL3102941)Copy SMILESCopy InChI

Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
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TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL

LigandBDBM50445242(CHEMBL3102941)Copy SMILESCopy InChI

Affinity DataIC50: 24nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/17/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL