BDBM50445005 CHEMBL3099944

SMILES COc1ccc(NC(=O)NC2CC2)c(OC[C@@H](O)CN2CCC3(Cc4cc(Cl)ccc4O3)CC2)c1

InChI Key InChIKey=XSDAUYLGCBWDAK-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445005   

TargetMacrophage inflammatory protein-1 alpha receptor(Rat)
Astrazeneca

Curated by ChEMBL

LigandBDBM50445005(CHEMBL3099944)Copy SMILESCopy InChI

Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MIP-1alpha from rat CCR1More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50445005(CHEMBL3099944)Copy SMILESCopy InChI

Affinity DataIC50: 1.80nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL