BDBM50444609 CHEMBL3099895

SMILES COc1ccc(CNC(=O)c2cc(cnc2-c2cccnc2)-c2cc(F)cc(F)c2)cc1OC

InChI Key InChIKey=KEBWWKOJTZNCBZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444609   

TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444609(CHEMBL3099895)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]SB-674042 from human orexin-2 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50444609(CHEMBL3099895)
Affinity DataKi:  5.15E+3nMAssay Description:Displacement of [3H]SB-674042 from human orexin-1 receptor after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed