BDBM50444295 CHEMBL3093806

SMILES CC(C)(C)C(=O)Oc1cn(c(CSc2nc3cc(ccc3o2)C(O)=O)cc1=O)-c1ccccc1

InChI Key InChIKey=SXFSYTYYYGDVGV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444295   

TargetKallikrein-1(Human)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50444295(CHEMBL3093806)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human kallikrein using H-Pro-Phe-Arg-AMC acetate salt as substrate measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCathepsin G(Human)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50444295(CHEMBL3093806)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human cathepsin G using Suc-Ala-Ala-Pro-Phe-p-nitroanilide as substrate incubated for 30 mins prior to substrate addition measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMyeloblastin(Human)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50444295(CHEMBL3093806)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human proteinase 3 using N-MeOSuc-Ala-Ala-Pro-Val-p-nitroanilide as substrate measured for 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50444295(CHEMBL3093806)
Affinity DataIC50: 80nMAssay Description:Inhibition of human neutrophil elastase using MeO-Suc-Ala-Ala-Pro-Val-AMC as substrate incubated for 30 mins prior to substrate addition measured for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed