BDBM50443586 CHEMBL3091975

SMILES CS(=O)(=O)OC1C[C@@H]2CCCC[C@@H]2[C@H]1\C=C\c1ccc(cn1)-c1cccc(F)c1

InChI Key InChIKey=WJCRFDMJISZXHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443586   

TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50443586(CHEMBL3091975)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50443586(CHEMBL3091975)
Affinity DataIC50: 6.40nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed