BDBM50443580 CHEMBL3091993

SMILES CC1(C[C@@H]2CCCC[C@@H]2[C@H]1C=Cc1ccc(cn1)-c1cccc(F)c1)OC(N)=O

InChI Key InChIKey=BUPBXZWQINIBSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443580   

TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50443580(CHEMBL3091993)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at PAR1 in human platelet rich plasma assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50443580(CHEMBL3091993)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at PAR1 in washed human platelets assessed as inhibition of haTRAP-induced platelet aggregation preincubated for 1 hr followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Korea Research Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50443580(CHEMBL3091993)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]haTRAP from PAR1 in human platelet membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed