BDBM50443560 CHEMBL3091723

SMILES C[C@@H](Oc1cc(cnc1N)-c1ccc2c(NC(=O)C22CCN(C)CC2)c1)c1c(Cl)ccc(F)c1Cl

InChI Key InChIKey=PIRWRQQYRXWTII-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50443560   

TargetTyrosine-protein kinase receptor UFO(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50443560(CHEMBL3091723)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of full-length AXL (unknown origin) phosphorylation expressed in MEF after 90 mins by Sandwich-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50443560(CHEMBL3091723)
Affinity DataIC50: 39nMAssay Description:Inhibition of NPM-fused ALK phosphorylation (unknown origin) expressed in human karpas 299 cells after 90 mins by Sandwich-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50443560(CHEMBL3091723)
Affinity DataIC50: 22nMAssay Description:Inhibition of c-Met phosphorylation in human MKN845 cells after 90 mins by Sandwich-ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50443560(CHEMBL3091723)
Affinity DataIC50: 29nMAssay Description:Inhibition of human AXL (unknown origin) using EAIYAAPFAKKK peptide as substrate by nanoliter kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50443560(CHEMBL3091723)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human c-Met using KKKSPGEYVNIEFG peptide as substrate by nanoliter kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50443560(CHEMBL3091723)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Met phosphorylation in human MKN845 cells after 1 hr by western blottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed