BDBM50443289 CHEMBL3088217

SMILES CC1CN(C(C)CN1C[C@@]1(O)CC[C@@]2(C)[C@@H](CC[C@H]3[C@@H]4CCC(=O)[C@@]4(C)CC[C@H]23)C1)S(=O)(=O)c1ccccc1C(F)(F)F

InChI Key InChIKey=IYHGEKFCMCXIEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443289   

Target17-beta-hydroxysteroid dehydrogenase type 3(Rat)
Laval University

Curated by ChEMBL
LigandPNGBDBM50443289(CHEMBL3088217)
Affinity DataIC50: 14nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomal fraction using [14C]-4-androstene-3,17-dione as substrate assessed as testosterone formation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50443289(CHEMBL3088217)
Affinity DataIC50: 90nMAssay Description:Inhibition of 17beta-HSD3 (unknown origin) expressed in human LNCAP cells assessed as reduction in [14C]-testosterone formation from [14C]-4-androste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rat)
Laval University

Curated by ChEMBL
LigandPNGBDBM50443289(CHEMBL3088217)
Affinity DataIC50: 80nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testes microsomal fraction assessed as reduction in [14C]-testosterone formation from [14C]-4-androst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed