BDBM50443132 CHEMBL3086175::US9221797, 42

SMILES O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N

InChI Key InChIKey=UURBEBBVEFUFRK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443132   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443132(CHEMBL3086175 | US9221797, 42)
Affinity DataIC50: 1.43nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
Go to US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50443132(CHEMBL3086175 | US9221797, 42)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50443132(CHEMBL3086175 | US9221797, 42)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed