BDBM50442946 CHEMBL3087191

SMILES COc1nn(C(C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1

InChI Key InChIKey=VIOUIMQQZZCOFQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50442946   

TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442946(CHEMBL3087191)
Affinity DataIC50: 631nMAssay Description:Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442946(CHEMBL3087191)
Affinity DataIC50: 630nMAssay Description:Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442946(CHEMBL3087191)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442946(CHEMBL3087191)
Affinity DataIC50: 115nMAssay Description:Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442946(CHEMBL3087191)
Affinity DataIC50: 11nMAssay Description:Inhibition of FAAH in rat RBL2H3 cells assessed as blockade of [3H]-anandamide uptake incubated for 15 mins prior to [3H]-anandamide addition measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed