BDBM50442944 CHEMBL3087171

SMILES COc1nn([C@H](C)c2ccc(cc2)N(c2ccccc2)c2ccccc2)c(=O)o1

InChI Key InChIKey=VIOUIMQQZZCOFQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50442944   

TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442944(CHEMBL3087171)
Affinity DataIC50: 339nMAssay Description:Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442944(CHEMBL3087171)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant MAGL overexpressed in HEK cells using 2-AG as substrate preincubated for 10 mins before substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442944(CHEMBL3087171)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Eastern Finland

Curated by ChEMBL
LigandPNGBDBM50442944(CHEMBL3087171)
Affinity DataIC50: 6.17E+3nMAssay Description:Inhibition of human recombinant FAAH overexpressed in African green monkey COS7 cells using [3H]-anandamide as substrate preincubated for 10 mins bef...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed