BDBM50442859 CHEMBL2441218

SMILES CCOC(=O)C1CCN(CC1)c1ccc(NC(=O)c2oc(nc2C(F)(F)F)-c2ccccc2)cn1

InChI Key InChIKey=AAGGKZQYACEUHR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442859   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442859(CHEMBL2441218)
Affinity DataIC50: 84nMAssay Description:Inhibition of human DGAT-1 expressed in insect Sf9 cell microsomes using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA as substrate after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed