BDBM50442793 CHEMBL239274

SMILES [O-][N+](=O)c1ccc2n(-c3ccc(Cl)cc3)c3nc(=O)[nH]c(=O)c3cc2c1

InChI Key InChIKey=NGFVSPNFZJSTPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442793   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50442793(CHEMBL239274)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50442793(CHEMBL239274)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50442793(CHEMBL239274)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed