BDBM50442785 CHEMBL2440444

SMILES FC(F)(F)c1cccc2cc3c(nc(=O)[nH]c3=O)n(-c3ccc(Cl)cc3)c12

InChI Key InChIKey=QOOGGDZVCDQTKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442785   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50442785(CHEMBL2440444)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of GST-tagged HDM2 (unknown origin) assessed as p53 ubiquitination by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed