BDBM50442745 CHEMBL2442996

SMILES COc1ccc(cc1)-c1ccccc1N1CCN(CCCCCC(=O)NCc2ccncc2)CC1

InChI Key InChIKey=SKEMXKKWOARREN-UHFFFAOYSA-N

Data  4 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50442745   

Target5-hydroxytryptamine receptor 7(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50442745(CHEMBL2442996)
Affinity DataKd:  1.20nMAssay Description:Displacement of [3H]5-CT from human 5HT7 receptor transfected in HEK293 cells after 60 mins by Scatchard plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50442745(CHEMBL2442996)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]5-CT from human 5HT7 receptor transfected in HEK293 cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50442745(CHEMBL2442996)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-prazosin from rat brain alpha1 adrenergic receptor after 50 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50442745(CHEMBL2442996)
Affinity DataKi:  239nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor transfected in HEK293-EBNA cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50442745(CHEMBL2442996)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed