BDBM50442677 CHEMBL2442304

SMILES NCCNc1ccn2ncc(-c3ccc4[nH]c(=O)[nH]c4c3)c2n1

InChI Key InChIKey=QUUBUYOWQZWVPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442677   

TargetSerine/threonine-protein kinase pim-2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442677(CHEMBL2442304)
Affinity DataIC50: 19nMAssay Description:Inhibition of Pim2 (unknown origin) using STK1 as substrate preincubated for 30 mins followed by substrate and ATP addition after 60 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442677(CHEMBL2442304)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of Pim1 (unknown origin) using STK3 as substrate preincubated for 30 mins followed by substrate and ATP addition after 45 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed