BDBM50442675 CHEMBL2442307

SMILES NCCNc1ccn2ncc(-c3cccc(c3)-c3ccccc3)c2n1

InChI Key InChIKey=MESLRIMNHFRXEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442675   

TargetSerine/threonine-protein kinase pim-2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442675(CHEMBL2442307)
Affinity DataIC50: 137nMAssay Description:Inhibition of Pim2 (unknown origin) using STK1 as substrate preincubated for 30 mins followed by substrate and ATP addition after 60 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50442675(CHEMBL2442307)
Affinity DataIC50: 10nMAssay Description:Inhibition of Pim1 (unknown origin) using STK3 as substrate preincubated for 30 mins followed by substrate and ATP addition after 45 mins by HTRF ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed