BDBM50442649 CHEMBL2441929

SMILES C[C@@H]1CC[C@H]([C@@H](C1)C(=O)Nc2ccc(cc2)OC)C(C)C

InChI Key InChIKey=HNSGVPAAXJJOPQ-UHFFFAOYSA-N

Data  2 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442649   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50442649(CHEMBL2441929)Copy SMILESCopy InChI

Affinity DataEC50:  40nMAssay Description:Inhibition of human TRPM8 (unknown origin) expressed in HEK293 cells assessed as inhibition of WS12-induced Ca2+ elevation by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50442649(CHEMBL2441929)Copy SMILESCopy InChI

Affinity DataEC50:  1.20E+4nMAssay Description:Agonist activity at TRPM8 (unknown origin) by fluorometric imaging plate reader analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL