BDBM50442415 CHEMBL2440148

SMILES Fc1cccc2C(=O)CC3(CCN(CC3)C(=O)Nc3ccc(OC(F)(F)F)cc3)Oc12

InChI Key InChIKey=CVVCHRQNLMNBBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442415   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Glenmark Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442415(CHEMBL2440148)
Affinity DataIC50: 182nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced 45Ca2+ uptake incubated for 10 mins prior to icili...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed