BDBM50442403 CHEMBL494252

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c2occ(-c3ccc(-[#8])cc3)c(=O)c2c1-[#8]

InChI Key InChIKey=RBZDYCGMMXHXJV-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50442403   

TargetPancreatic triacylglycerol lipase(Pig)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50442403(CHEMBL494252)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of porcine pancreatic lipase assessed as hydrolysis of p-NPB to p-nitrophenol by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qiqihar University

Curated by ChEMBL
LigandPNGBDBM50442403(CHEMBL494252)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442403(CHEMBL494252)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of Clostridium perfringens neuraminidase using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qiqihar University

Curated by ChEMBL
LigandPNGBDBM50442403(CHEMBL494252)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of recombinant human PTP1B (1 to 321 residues) expressed in Escherichia coli using p-nitrophenyl phosphate as substrate incubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50442403(CHEMBL494252)
Affinity DataKi:  4.29E+3nMAssay Description:Non-competitive inhibition of Clostridium perfringens neuraminidase using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Qiqihar University

Curated by ChEMBL
LigandPNGBDBM50442403(CHEMBL494252)
Affinity DataKi:  9.60E+3nMAssay Description:Non-competitive inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate by spectrophotometry based Lineweaver-Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2017
Entry Details Article
PubMed