BDBM50441224 CHEMBL2431015

SMILES ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc(Br)c2)cc1

InChI Key InChIKey=YGTYRNSBOZPWFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441224   

TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441224(CHEMBL2431015)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50441224(CHEMBL2431015)
Affinity DataIC50: 104nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed