BDBM50441222 CHEMBL2431017

SMILES ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc(OC(F)(F)F)c2)cc1

InChI Key InChIKey=RMRVSLSYZNRHKL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441222   

TargetMatrix metalloproteinase-14(Human)
UniversitÀ

Curated by ChEMBL
LigandPNGBDBM50441222(CHEMBL2431017)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human MMP-14 catalytic domain using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 4 hrs measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50441222(CHEMBL2431017)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human ADAM-17 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate incubated for 30 mins measured every 15 secs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed