BDBM50441010 CHEMBL2430143::US9732037, Compound 14
SMILES Cc1cc(nc(c1)N)COC[C@H](CN)OCc2cc(cc(n2)N)C
InChI Key InChIKey=FVCUZJIKIIWHJD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50441010
TargetNitric oxide synthase oxygenase(Bacillus subtilis (strain 168))
University of California Irvine
University of California Irvine
Affinity DataKd: 1.87E+4nMAssay Description:In short, the difference between the imidazole-bound low-spin peak at 430 nm and the inhibitorbound high-spin peak at 395 nm was measured as a functi...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 382nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli using L-arginine as substrate up to 180 seconds by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataKi: 382nMAssay Description:NOS inhibition assays of representative compounds 1-21 were undertaken, and the results are summarized in Table 1, below. All NOS isoforms were expre...More data for this Ligand-Target Pair
Affinity DataKi: 2.64E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli using L-arginine as substrate up to 180 seconds by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.64E+4nMAssay Description:NOS inhibition assays of representative compounds 1-21 were undertaken, and the results are summarized in Table 1, below. All NOS isoforms were expre...More data for this Ligand-Target Pair
Affinity DataKi: 4.08E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli using L-arginine as substrate up to 180 seconds by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.08E+4nMAssay Description:NOS inhibition assays of representative compounds 1-21 were undertaken, and the results are summarized in Table 1, below. All NOS isoforms were expre...More data for this Ligand-Target Pair