BDBM50440869 CHEMBL2431727

SMILES NCCCC[C@H](NC(=O)CNC(=O)Nc1ccc2n(Cc3c(Cl)cccc3Cl)cc(CN3CCCC3)c2c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=ADEQJSQZZXWZPW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440869   

TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440869(CHEMBL2431727)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human PAR2 expressed in human NCTC-2544 cells assessed as inhibition of SLIGKV-NH2-induced NFkappaB activation preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440869(CHEMBL2431727)
Affinity DataKi:  600nMAssay Description:Displacement of [3H]2-furoyl-LIGRL-NH2 from human PAR2 expressed in human NCTC-2544 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440869(CHEMBL2431727)
Affinity DataKi:  670nMAssay Description:Binding affinity to PAR2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed