BDBM50440868 CHEMBL2431617

SMILES CC[C@H](C)[C@@H](C(=O)N1CCC2(CC1)C=Cc3c2cccc3)NC(=O)[C@H](CC4CCCCC4)NC(=O)c5ccno5

InChI Key InChIKey=DCUDDCGUKZLQLN-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50440868   

TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at protease-activated receptor 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced ca2+ release preincubated for 15 mins measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 9.60E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced ca2+ release preincubated for 15 mins measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.25E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-stimulated intracellular calcium release preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of endogenous trypsin-stimulated intracellular calcium release by Fluo-3 AM d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-stimulated intracellular calcium release preincubated for 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2018
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50440868(CHEMBL2431617)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of agonist-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed