BDBM50440862 CHEMBL2431717

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1ccccc1OC

InChI Key InChIKey=CVXCZFZFHKSABI-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50440862   

TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 4.50E+3nMAssay Description:Displacement of europium-labeled 2f-LIGRLO-NH2 from human PAR2 expressed in CHO cells after 1 to 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced ca2+ release preincubated for 15 mins measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced ca2+ release preincubated for 15 mins measured after 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 501nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 500nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced ca2+ release preincubated for 15 mins measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2017
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of 2f-LIGRLO-NH2-induced intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at PAR2 in human HT-29 cells assessed as inhibition of trypsin-induced intracellular calcium releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50440862(CHEMBL2431717)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at PAR2 in human EAhy926 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilization pretreated for 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed