BDBM50440693 CHEMBL2430983

SMILES Cn1nc(cc1NC(=O)[C@H](Cc1ccccc1)NCC(O)=O)-c1ccncc1

InChI Key InChIKey=LWMQAANXGYCZIW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50440693   

TargetProbable G-protein coupled receptor 142(Human)
Amgen

Curated by ChEMBL

LigandBDBM50440693(CHEMBL2430983)Copy SMILESCopy InChI

Affinity DataEC50:  52nMAssay Description:Agonist activity at human GPR142 expressed in HEK293 cells assessed as inositol phosphate accumulation using [3H]-inositol after 1 hr by scintillatio...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetCytochrome P450 2D6(Human)
Amgen

Curated by ChEMBL

LigandBDBM50440693(CHEMBL2430983)Copy SMILESCopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetProbable G-protein coupled receptor 142(Mouse)
Amgen

Curated by ChEMBL

LigandBDBM50440693(CHEMBL2430983)Copy SMILESCopy InChI

Affinity DataEC50:  31nMAssay Description:Agonist activity at mouse GPR142More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL