BDBM50440607 CHEMBL2426375

SMILES CCN1Cc2ccc(NC(=O)c3ccc(cc3)C(=O)N3CCC(CC3)C3CCCN3)cc2C1

InChI Key InChIKey=OBWFOTDCVMCZMZ-UHFFFAOYSA-N

Data  11 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50440607   

TargetScm-like with four MBT domains protein 1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 160nMAssay Description:Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPHD finger protein 23(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PHF23 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 170nMAssay Description:Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 4(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL4 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataKd:  6.80E+4nMAssay Description:Binding affinity to L3MBTL1 (unknown origin) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataKd:  470nMAssay Description:Binding affinity to L3MBTL3 (unknown origin) by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JARID1A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase UHRF1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of UHRF1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChromobox protein homolog 7(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CBX7 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMBT domain-containing protein 1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440607(CHEMBL2426375)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed