BDBM50440470 CHEMBL2425883::US20240115577, Compound 24

SMILES CC#CCn1c(cc(=O)n(Cc2ccccc2)c1=O)N1CCC[C@@H](N)C1

InChI Key InChIKey=GEASAYGDKVRAMO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50440470   

TargetDipeptidyl peptidase 9(Human)
First Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50440470(CHEMBL2425883 | US20240115577, Compound 24)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
First Affiliated Hospital of Guangzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50440470(CHEMBL2425883 | US20240115577, Compound 24)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of DPP-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50440470(CHEMBL2425883 | US20240115577, Compound 24)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant DPP4 using Gly-Pro-AMC as substrate preincubated for 15 mins followed by substrate addition and measured for 20 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Sichuan Normal University

Curated by ChEMBL
LigandPNGBDBM50440470(CHEMBL2425883 | US20240115577, Compound 24)
Affinity DataIC50: 3nMAssay Description:Human DPP4 activity assay data were obtained using a DPP4 Activity Assay Kit (Sigma-Aldrich, MAK088) according to the manufacturer's instructions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
Go to US Patent