BDBM50440092 CHEMBL2426085

SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Br)cc1)c1c(-c2ccccc2)c2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=XMGDSIFIWYIZOF-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50440092   

TargetGlutamate receptor ionotropic, NMDA 2D(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440092(CHEMBL2426085)
Affinity DataIC50: 3.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2C(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440092(CHEMBL2426085)
Affinity DataIC50: 3.60E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Emory University

Curated by ChEMBL
LigandPNGBDBM50440092(CHEMBL2426085)
Affinity DataIC50: 2.20E+4nMAssay Description:Negative allosteric modulation of recombinant rat GluN2B receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetDNA repair protein RAD51 homolog 1(Human)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50440092(CHEMBL2426085)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of biotinylated BRC4 peptide binding to His-tagged human RAD51 expressed in Escherichia coli Rosetta(DE3) pLysS cells assessed as BRC4-RAD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed