BDBM50440045 CHEMBL2425952

SMILES CCc1nc2c(Cc3ccc(cc3)C(=O)NO)cccc2c(=O)n1CCc1ccccc1

InChI Key InChIKey=HPCPCLJRBNRLLW-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50440045   

TargetCytochrome P450 1A2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using 3-cyano-7-ethoxycoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin) using 3-cyano-7-ethoxycoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of CYP2C19 (unknown origin) using 3-cyano-7-ethoxycoumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin) using Vivid OOMR as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human HDAC1 expressed in baculovirus expression system in Sf9 cells using RHKKAc (379 to 382 residues) fluorogenic peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 79nMAssay Description:Inhibition of human HDAC6 expressed in baculovirus expression system in Sf9 cells using RHKKAc (379 to 382 residues) fluorogenic peptide as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50440045(CHEMBL2425952)
Affinity DataIC50: 282nMAssay Description:Inhibition of human HDAC8 expressed in baculovirus expression system in Sf9 cells using RHKAcKAc (379 to 382 residues) fluorogenic peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed