BDBM50439807 CHEMBL2419718::US9227982, 4

SMILES Fc1ccccc1CCC(=O)N(Cc1cccs1)Cc1nc2CCOCc2c(=O)[nH]1

InChI Key InChIKey=HVPUASJORDGFQX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439807   

LigandPNGBDBM50439807(CHEMBL2419718 | US9227982, 4)
Affinity DataIC50: 64nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

LigandPNGBDBM50439807(CHEMBL2419718 | US9227982, 4)
Affinity DataIC50: 271nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439807(CHEMBL2419718 | US9227982, 4)
Affinity DataIC50: 304nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed