BDBM50439683 CHEMBL2418221

SMILES [#6]-[#6@@H](-[#8])-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#8])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6]-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](-[#8])=O

InChI Key InChIKey=DGXVRVIKQDYUDK-UHFFFAOYSA-N

Data  7 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50439683   

TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of alphaVbeta3 integrin-mediated human SK-MEL-24 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 930nMAssay Description:Inhibition of alpha5beta1 integrin-mediated human K562 cell adhesion to fibronectin incubated for 30 mins before plating measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 926nMAssay Description:Antagonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at alphaVbeta5 in human MCF7 cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta6 in human HT-29 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronecti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-6(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at alphaVbeta6 in human HT-29 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-5/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 0.670nMAssay Description:Antagonist activity at alpha5beta1 in human K562 cells assessed as reduction in cell adhesion to fibronectin pre-incubated for 30 mins before fibrone...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at alpha2bbeta3 in human HEL cells assessed as reduction in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinog...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed