BDBM50439614 CHEMBL2419309

SMILES CC1N(C)C(=O)C(=C1c1ccc2OCC(=O)Nc2c1)c1ccc(F)cc1

InChI Key InChIKey=NZDONLCAMPFJHQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439614   

TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50: 61nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439614(CHEMBL2419309)
Affinity DataIC50: 2.10E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed