BDBM50439607 CHEMBL2419301

SMILES CC1NC(=O)C(=C1c1cc(C)c2OCC(=O)Nc2c1)c1ccc(F)cc1

InChI Key InChIKey=DBJLPZIAKOMATO-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50439607   

TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]aldosterone from human mineralocorticoid receptor expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human mineralocorticoid receptor expressed in COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]testosterone from androgen receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [[3H]-Progesterone from progesterone receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]-Dexamethasone from glucocorticoid receptor (unknown origin) expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 83nMAssay Description:Antagonist activity at MR (unknown origin) expressed in COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]-Aldosterone from human MR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-Progesterone from human PR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-Testosterone from human AR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50439607(CHEMBL2419301)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]-Dexamethasone human GR expressed in 293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed