BDBM50439496 CHEMBL2418096::US9169182, J23

SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl

InChI Key InChIKey=MKTUZAYNCRKLDS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50439496   

TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Bacillus subtilis)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of Bacillus subtilis FtsZ GTPase activity assessed as production of inorganic phosphate measured up to 60 mins by malachite green-phosphom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 4.40E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
Go to US Patent

TargetCell division protein FtsZ(Escherichia coli (strain K12))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.60E+4nMpH: 6.5 T: 2°CAssay Description:GTPase assays were performed in 50 mM MES, pH 6.5, 50 mM KCl, 5 mM MgCl2 in the presence of 2 uM FtsZ in the presence of varying concentrations of co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
Go to US Patent

TargetCell division protein FtsZ(Staphylococcus aureus)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of Staphylococcus aureus FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetCell division protein FtsZ(Escherichia coli (strain K12))
The United States of America, As Represented By The Secretary, Department of Health and Human Services

US Patent
LigandPNGBDBM50439496(CHEMBL2418096 | US9169182, J23)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed