BDBM50439475 CHEMBL2417905

SMILES COc1ccc(-c2ccc(cc2C(O)=O)C(=O)NCC(C)(C)C)c(n1)C(=O)Nc1ccc(cc1)C(N)=N

InChI Key InChIKey=CATVOBGLOJBTJR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439475   

TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439475(CHEMBL2417905)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human tissue plasminogen activator using spectrozyme tissue plasminogen activator as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439475(CHEMBL2417905)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human F11a using S-2366 as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439475(CHEMBL2417905)
Affinity DataIC50: 100nMAssay Description:Inhibition of human F10a using S-2222 as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50439475(CHEMBL2417905)
Affinity DataIC50: 11nMAssay Description:Inhibition of human F7a using D-Ile-Pro-Arg-AFC as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed