BDBM50439218 CHEMBL2418809

SMILES CC1CCCN(C1C)C(=O)c1nc(Nc2cc3OCOc3cc2F)sc1Cl

InChI Key InChIKey=GGKQWFQQUMWVOB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439218   

TargetShort transient receptor potential channel 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439218(CHEMBL2418809)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetShort transient receptor potential channel 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439218(CHEMBL2418809)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed