BDBM50438853 CHEMBL2420475

SMILES CS(=O)(=O)Nc1cccc(c1)-n1c2ccccc2cc2c1nc(=O)[nH]c2=O

InChI Key InChIKey=VEXGASXJDARWTC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438853   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50438853(CHEMBL2420475)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of APE-1 (unknown origin) using double-stranded AP-site containing DNA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
University of Manchester

Curated by ChEMBL
LigandPNGBDBM50438853(CHEMBL2420475)
Affinity DataEC50:  4.66E+3nMAssay Description:Inhibition of TDP2 (unknown origin) using 4-nitrophenyl phenylphosphonate as substrate after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed