BDBM50438821 CHEMBL2413368

SMILES CN1CCOc2c1cccc2C(=O)NCC1CCN1C(=O)c1nc(C)sc1-c1cccc(C)c1

InChI Key InChIKey=CMCZEHNAHKHERX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438821   

TargetOrexin receptor type 2(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50438821(CHEMBL2413368)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human orexin receptor 2 expressed in CHO cells assessed as inhibition of orexin-A-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50438821(CHEMBL2413368)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human orexin receptor 1 expressed in CHO cells assessed as inhibition of orexin-A-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed