BDBM50438539 CHEMBL2414860

SMILES COc1ccc(C=NNC(=O)Nc2ccncc2)cc1OC

InChI Key InChIKey=BUYKIHNWCJPNLT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50438539   

TargetCholinesterase(Human)
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438539(CHEMBL2414860)
Affinity DataIC50: 4.26E+5nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438539(CHEMBL2414860)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438539(CHEMBL2414860)
Affinity DataKi:  1.03E+4nMAssay Description:Competitive inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCholinesterase(Human)
Banaras Hindu University

Curated by ChEMBL
LigandPNGBDBM50438539(CHEMBL2414860)
Affinity DataKi:  2.83E+5nMAssay Description:Competitive inhibition of human serum BChE using butyrylthiocholine iodide as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed