BDBM50438169 CHEMBL2409870

SMILES OC[C@H]1C[C@H](O)CN1CCCc1ccc(Nc2nc(cs2)-c2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=GMGHOLUNDWPBND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438169   

TargetSphingosine kinase 2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438169(CHEMBL2409870)
Affinity DataIC50: 90nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50438169(CHEMBL2409870)
Affinity DataIC50: 30nMAssay Description:Inhibition of purified human SphK1 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed