BDBM50437478 CHEMBL2409475

SMILES CNC(=O)[C@@H]1C[C@H]2CNC[C@H](C2)C1

InChI Key InChIKey=HCZNYXWSHKDVMC-UHFFFAOYSA-N

Data  1 KI  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437478   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50437478(CHEMBL2409475)Copy SMILESCopy InChI

Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at alpha4beta2 nACHR in human SHEP1 cell membranes assessed as stimulation of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50437478(CHEMBL2409475)Copy SMILESCopy InChI

Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]Nicotine from alpha4beta2 nACHR in human SHEP1 cell membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL