BDBM50437476 CHEMBL2409497

SMILES COC(=O)N1CC2CNCC(C2)C1

InChI Key InChIKey=MRSAIDFRTZWWBE-UHFFFAOYSA-N

Data  1 KI  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437476   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50437476(CHEMBL2409497)Copy SMILESCopy InChI

Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at alpha4beta2 nACHR in human SHEP1 cell membranes assessed as stimulation of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50437476(CHEMBL2409497)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Displacement of [3H]Nicotine from alpha4beta2 nACHR in human SHEP1 cell membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL