BDBM50437370 CHEMBL3037912

SMILES COc1cc(nc2c(F)c(ccc12)-c1nc([C@H]2C[C@@](C)(O)C2)n2ccnc(N)c12)-c1ccccc1

InChI Key InChIKey=XTSWSMBDXLBRMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437370   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50437370(CHEMBL3037912)
Affinity DataIC50: 4nMAssay Description:Inhibition of full length human IGF-1R overexpressed in mouse NIH 3T3 cells assessed as IGF1-induced protein phosphorylation incubated for 2 hrs prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed