BDBM50437232 3‐(3‐carbamoylphenyl)‐4‐methoxyphenyl N‐ cyclohexylcarbamate (Compound 3)::CHEMBL2402921::US9187413, 1c

SMILES COc1ccc(OC(=O)NC2CCCCC2)cc1-c1cccc(c1)C(N)=O

InChI Key InChIKey=ADPPJKSMKLENRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50437232   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50437232(CHEMBL2402921 | 3‐(3‐carbamoylphenyl)&...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Wistar rat brain FAAH using [3H]-ethanolamine as substrate preincubated for 20 mins followed by substrate addition by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [33-574](Rat)
Fondazione Istituto Italiano Di Tecnologia

LigandPNGBDBM50437232(CHEMBL2402921 | 3‐(3‐carbamoylphenyl)&...)
Affinity DataIC50: 137nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2014
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50437232(CHEMBL2402921 | 3‐(3‐carbamoylphenyl)&...)
Affinity DataIC50: 45.3nMAssay Description:The assays for compounds described herein are amenable to high throughput screening. Preferred assays thus detect binding of the inhibitor to FAAH or...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2016
Entry Details
Go to US Patent