BDBM50437209 CHEMBL2402734

SMILES COc1cc(NC(=O)[C@@H]2N[C@@H](CC(C)(C)C)[C@@](C#N)([C@H]2c2cccc(Cl)c2F)c2ccc(Cl)cc2F)ccc1C(O)=O

InChI Key InChIKey=QFSQODXTNHWKSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437209   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50437209(CHEMBL2402734)
Affinity DataIC50: 20nMAssay Description:Binding affinity to GST-tagged MDM2 (unknown origin) assessed as inhibition of interaction with p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed